Clofarabine Has a Superior Therapeutic Window as compared to Gemcitabine in Preclinical Bladder Cancer Models.
Gutmann M, Ertl IE, Herek P, Vician P, Pirker C, Nössing C, Brettner R, Lemberger U, Grausenburger R, Batlogg K, Baumfried O, Prantl I, Singh N, Laukhtina E, Oszwald A, Wasinger G, Compérat E, Berger W, Shariat SF, Englinger B.Eur Urol Oncol. 2024 May 15:S2588-9311(24)00115-9. doi: 10.1016/j.euo.2024.05.001. Online ahead of print.
PMID: 38755094
Recent contributions of single-cell and spatial profiling to the understanding of bladder cancer.
Grausenburger R, Herek P, Shariat SF, Englinger B.Curr Opin Urol. 2024 Jul 1;34(4):236-243. doi: 10.1097/MOU.0000000000001183. Epub 2024 Apr 22.
PMID: 38650456
Preclinical models for bladder cancer therapy research.
Ertl I, Shariat SF, Berger W, Englinger B.Curr Opin Urol. 2024 Jul 1;34(4):244-250. doi:10.1097/MOU.0000000000001182. Epub 2024 Apr 16.
PMID: 38630912
Molecular research in bladder cancer.
Englinger B.Curr Opin Urol. 2024 Jul 1;34(4):225-226. doi: 10.1097/MOU.0000000000001181. Epub 2024 Apr 15.
PMID: 38607277
Advances in preclinical assessment of therapeutic targets for bladder cancer precision medicine.
Nössing C, Herek P, Shariat SF, Berger W, Englinger B.Curr Opin Urol. 2024 Jul 1;34(4):251-257. doi: 10.1097/MOU.0000000000001177. Epub 2024 Apr 10.
PMID: 38602053
Clinically relevant molecular hallmarks of PFA ependymomas display intratumoral heterogeneity and correlate with tumor morphology.
Gödicke S, Kresbach C, Ehlert M, Obrecht D, Altendorf L, Hack K, von Hoff K, Carén H, Melcher V, Kerl K, Englinger B, Filbin M, Pajtler KW, Gojo J, Pietsch T, Rutkowski S, Schüller U.Acta Neuropathol. 2024 Jan 24;147(1):23. doi: 10.1007/s00401-023-02682-x.
PMID: 38265527
Re: The Complete Sequence of a Human Y Chromosome.
Englinger B, Shariat SF.Eur Urol. 2024 Apr;85(4):393. doi: 10.1016/j.eururo.2023.11.011. Epub 2023 Nov 25.
PMID: 38007312
Intracellular remodeling associated with endoplasmic reticulum stress modifies biomechanical compliance of bladder cells.
Gruber L, Jobst M, Kiss E, Karasová M, Englinger B, Berger W, Del Favero G.Cell Commun Signal. 2023 Oct 30;21(1):307. doi: 10.1186/s12964-023-01295-x.
PMID: 37904178
The microbiome of kidney stones and urine of patients with nephrolithiasis
Ursula Lemberger, Petra Pjevac, Bela Hausmann, David Berry, Daniel Moser, Victoria Jahrreis, Mehmet Özsoy, Shahrokh F Shariat, Julian Veser
2023 Jan 4;51(1):27. doi: 10.1007/s00240-022-01403-5.
PMID: 36596939
Molecular and Pharmacological Bladder Cancer Therapy Screening: Discovery of Clofarabine as a Highly Active Compound.
Ertl IE, Lemberger U, Ilijazi D, Hassler MR, Bruchbacher A, Brettner R, Kronabitter H, Gutmann M, Vician P, Zeitler G, Koren A, Lardeau CH, Mohr T, Haitel A, Compérat E, Oszwald A, Wasinger G, Clozel T, Elemento O, Kubicek S, Berger W, Shariat SF.Eur Urol.
2022 Sep;82(3):261-270. DOI: 10.1016/j.eururo.2022.03.009.
PMID: 35393162
Evaluation of APOBEC3 expression as prognostic marker in squamous cell carcinoma of the penis.
Trimmel B, Oszwald A, Diemand C, Ertl IE, Lemberger U, Bruchbacher A, Brettner R, Korn S, Resch I, Comperat E, Shariat SF, Hassler MR.Sci Rep.
2022 Jul 28;12(1):12911. doi: 10.1038/s41598-022-17056-8.
PMID: 35902635
Expression Analysis and Mutational Status of Histone Methyltransferase KMT2D at Different Upper Tract Urothelial Carcinoma Locations.
Laukhtina E, Lemberger U, Bruchbacher A, Ilijazi D, Korn S, Berndl F, D'Andrea D, Susani M, Enikeev D, Compérat E, Shariat SF, Hassler MR.J Pers Med.
2021 Nov 4;11(11):1147. doi: 10.3390/jpm11111147.
PMID: 34834500 Free PMC article.
Lipid droplet-mediated scavenging as novel intrinsic and adaptive resistance factor against the multikinase inhibitor ponatinib
Bernhard Englinger, Anna Laemmerer, Patrick Moser, Sebastian Kallus, Clemens Röhrl, Christine Pirker, Dina Baier, Thomas Mohr, Laura Niederstaetter, Samuel M Meier-Menches, Christopher Gerner, Lisa Gabler, Johannes Gojo, Gerald Timelthaler, Julia Senkiv, Walter Jäger, Christian R Kowol, Petra Heffeter, Walter Berger
2020 Sep 15;147(6):1680-1693. doi: 10.1002/ijc.32924. Epub 2020 Mar 2.
PMID: 32064608
Discovery of Molecular DNA Methylation-Based Biomarkers through Genome-Wide Analysis of Response Patterns to BCG for Bladder Cancer.
Ilijazi D, Pulverer W, Ertl IE, Lemberger U, Kimura S, Abufaraj M, D'Andrea D, Pradere B, Bruchbacher A, Graf A, Soria F, Susani M, Haitel A, Molinaro L, Pycha A, Comploj E, Pabinger S, Weinhäusel A, Egger G, Shariat SF, Hassler MR.Cells.
2020 Aug 5;9(8):1839. doi: 10.3390/cells9081839.
PMID: 32764425
Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma
Johannes Gojo, Bernhard Englinger, Li Jiang, Jens M Hübner, McKenzie L Shaw, Olivia A Hack, Sibylle Madlener, Dominik Kirchhofer, Ilon Liu, Jason Pyrdol, Volker Hovestadt, Emanuele Mazzola, Nathan D Mathewson, Maria Trissal, Daniela Lötsch, Christian Dorfer, Christine Haberler, Angela Halfmann, Lisa Mayr, Andreas Peyrl, Rene Geyeregger, Benjamin Schwalm, Monica Mauermann, Kristian W Pajtler, Till Milde, Marni E Shore, Jack E Geduldig, Kristine Pelton, Thomas Czech, Orr Ashenberg, Kai W Wucherpfennig, Orit Rozenblatt-Rosen, Sanda Alexandrescu, Keith L Ligon, Stefan M Pfister, Aviv Regev, Irene Slavc, Walter Berger, Mario L Suvà, Marcel Kool, Mariella G Filbin
2020 Jul 13;38(1):44-59.e9. doi: 10.1016/j.ccell.2020.06.004.
PMID: 32663469
The prognostic impact of tumour NSD2 expression in advanced prostate cancer.
Stangl-Kremser J and Lemberger U, Hassler MR, Garstka N, Grubmüller B, Haitel A, Enikeev DV, Glybochko PV, Kramer G, Susani M, Shariat SF.Biomarkers.
2020 May;25(3):268-273. doi: 10.1080/1354750X.2020.1734861. Epub 2020 Mar 2.
PMID: 32091270
Prevalence and Prognostic Value of the Polymorphic Variant 1245A>C of HSD3B1 in Castration-resistant Prostate Cancer.
Stangl-Kremser J, Lemberger U, Hassler MR, Bruchbacher A, Ilijazi D, Garstka N, Kramer G, Haitel A, Abufaraj M, Shariat SF.Clin Genitourin Cancer.
2019 Oct;17(5):389-394. doi: 10.1016/j.clgc.2019.06.012. Epub 2019 Jun 26.
PMID: 31331867
Metal Drugs and the Anticancer Immune Response
Bernhard Englinger, Christine Pirker, Petra Heffeter, Alessio Terenzi, Christian R Kowol, Bernhard K Keppler, Walter Berger
2019 Jan 23;119(2):1519-1624. doi: 10.1021/acs.chemrev.8b00396.
PMID: 30489072
Intrinsic fluorescence of the clinically approved multikinase inhibitor nintedanib reveals lysosomal sequestration as resistance mechanism in FGFR-driven lung cancer
Bernhard Englinger, Sebastian Kallus, Julia Senkiv, Daniela Heilos, Lisa Gabler, Sushilla van Schoonhoven, Alessio Terenzi, Patrick Moser, Christine Pirker, Gerald Timelthaler, Walter Jäger, Christian R Kowol, Petra Heffeter, Michael Grusch, Walter Berger
2017 Sep. doi: 10.1186/s13046-017-0592-3.7;36(1):122.
PMID: 28882160